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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCQ
All Species:
29.7
Human Site:
Y90
Identified Species:
43.56
UniProt:
Q04759
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04759
NP_006248.1
706
81865
Y90
S
E
T
T
V
E
L
Y
S
L
A
E
R
C
R
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
Y90
S
E
T
T
V
E
L
Y
S
L
A
E
R
C
R
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
S553
S
E
V
T
V
G
V
S
V
L
A
E
R
C
K
Dog
Lupus familis
XP_849292
706
81555
S90
S
E
T
T
V
E
L
S
S
L
A
E
R
C
R
Cat
Felis silvestris
Mouse
Mus musculus
Q02111
707
81555
Y90
S
E
T
T
V
E
L
Y
S
L
A
E
R
C
R
Rat
Rattus norvegicus
Q9WTQ0
707
81732
Y90
S
E
T
T
V
E
L
Y
S
L
A
E
R
C
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
Y90
S
E
T
T
V
E
L
Y
P
L
A
E
R
C
R
Chicken
Gallus gallus
NP_001006133
699
80179
S89
S
E
V
T
V
G
V
S
V
L
A
E
R
C
K
Frog
Xenopus laevis
Q7LZQ8
671
76506
P84
E
F
V
T
F
S
C
P
G
A
D
K
G
P
A
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
P92
C
P
G
A
D
K
G
P
A
S
D
D
P
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
T83
A
T
F
L
R
Q
P
T
F
C
S
H
C
R
E
Honey Bee
Apis mellifera
XP_394743
624
71014
G86
P
R
E
T
N
N
I
G
G
G
A
I
T
K
R
Nematode Worm
Caenorhab. elegans
P34722
704
80280
A88
N
Q
T
P
V
V
E
A
T
M
R
L
E
D
I
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
H82
R
K
A
K
V
H
E
H
R
G
H
K
F
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
R248
I
D
D
T
I
K
A
R
T
K
P
S
R
N
D
Red Bread Mold
Neurospora crassa
P87253
1142
127954
L170
L
S
Q
I
Q
F
K
L
N
V
E
E
Q
Y
L
Conservation
Percent
Protein Identity:
100
99.7
33.6
96.7
N.A.
94.7
94
N.A.
86.1
63.3
33.9
34.1
N.A.
42.9
43.2
47.1
47.8
Protein Similarity:
100
99.7
45.1
98.3
N.A.
97.5
96.8
N.A.
92.9
77.1
48.2
49.2
N.A.
58.7
58.9
64.1
62
P-Site Identity:
100
100
60
93.3
N.A.
100
100
N.A.
93.3
60
6.6
0
N.A.
0
20
13.3
6.6
P-Site Similarity:
100
100
73.3
93.3
N.A.
100
100
N.A.
93.3
73.3
13.3
20
N.A.
20
26.6
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.2
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.3
40.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
7
0
0
7
7
7
7
57
0
0
0
7
% A
% Cys:
7
0
0
0
0
0
7
0
0
7
0
0
7
50
0
% C
% Asp:
0
7
7
0
7
0
0
0
0
0
13
7
0
7
7
% D
% Glu:
7
50
7
0
0
38
13
0
0
0
7
57
7
0
7
% E
% Phe:
0
7
7
0
7
7
0
0
7
0
0
0
7
0
0
% F
% Gly:
0
0
7
0
0
13
7
7
13
13
0
0
7
0
0
% G
% His:
0
0
0
0
0
7
0
7
0
0
7
7
0
0
0
% H
% Ile:
7
0
0
7
7
0
7
0
0
0
0
7
0
0
7
% I
% Lys:
0
7
0
7
0
13
7
0
0
7
0
13
0
7
13
% K
% Leu:
7
0
0
7
0
0
38
7
0
50
0
7
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
7
0
0
0
7
7
0
0
7
0
0
0
0
7
0
% N
% Pro:
7
7
0
7
0
0
7
13
7
0
7
0
7
7
7
% P
% Gln:
0
7
7
0
7
7
0
0
0
0
0
0
7
0
0
% Q
% Arg:
7
7
0
0
7
0
0
7
7
0
7
0
57
13
44
% R
% Ser:
50
7
0
0
0
7
0
19
32
7
7
7
0
0
7
% S
% Thr:
0
7
44
69
0
0
0
7
13
0
0
0
7
7
0
% T
% Val:
0
0
19
0
63
7
13
0
13
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
32
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _